• Yuju Cheon Research Scholars Program, Harvard Student Agencies, In collaboration with Learn with Leaders


Oral Health, Cardiovascular Diseases, Gum Disease, Bacteria, Inflammation, Heart Health


The relationship between oral health and cardiovascular diseases (CVD) has gained significant attention in recent years. Emerging research suggests a potential connection between oral health, specifically gum disease, and the development of cardiovascular ailments such as heart attacks and strokes. Bacteria originating from oral infections can enter the bloodstream, leading to inflammation in the heart's blood vessels and infection in the heart valves. This literature review explores the link between oral health and cardiovascular diseases, highlighting the mechanisms underlying this association. Two previous studies are reviewed, emphasizing the impact of dental hygiene practices on heart health. It was found that the connection between oral health and cardiovascular diseases is evident and it is crucial for promoting overall well-being and underscores the importance of maintaining good oral hygiene.


I. “Arteriosclerosis / Atherosclerosis.” Mayo Clinic, 1 July 2022, www.mayoclinic.org/diseases-conditions/arteriosclerosis-atherosclerosis/symptoms-causes/syc-20350569#:~:text=When%20atherosclerosis%20narrows%20the%20arteries,heart%20attack%20or%20heart%20failure

II. “Bad Toothbrushing Habits Tied to Higher Heart Risk.” Www.Heart.Org, 16 Aug. 2021, www.heart.org/en/news/2018/11/07/bad-tooth-brushing-habits-tied-to-higher-heart-risk

III. Gao, S., Liu, Y., Duan, X., Liu, K., Mohammed, M., Gu, Z., Ren, J., Yakoumatos, L., Yuan, X., Lu, L., Liang, S., Li, J., Scott, D. A., Lamont, R. J., Zhou, F., & Wang, H. (2021). Porphyromonas gingivalis infection exacerbates oesophageal cancer and promotes resistance to neoadjuvant chemotherapy. British journal of cancer, 125(3), 433–444. https://doi.org/10.1038/s41416-021-01419-5

IV. How, Kah Yan, et al. “Porphyromonas Gingivalis: An Overview of Periodontopathic Pathogen below the Gum Line.” Frontiers in Microbiology, 9 Feb. 2016, www.ncbi.nlm.nih.gov/pmc/articles/PMC4746253/

V. Juneau, M. (2022, July 19). The influence of oral health on the risk of cardiovascular disease. Observatoire de la prévention. Retrieved April 23, 2023, from https://observatoireprevention.org/en/2022/03/27/the-influence-of-oral-health-on-the-risk-of-cardiovascular-disease/

VI. Lee, Sun Kyung, and Seon Young Hwang. “Oral Health in Adults with Coronary Artery Disease and Its Risk Factors: A Comparative Study Using the Korea National Health and Nutrition Examination Survey Data - BMC Cardiovascular Disorders.” BioMed Central, 4 Feb. 2021, bmccardiovascdisord.biomedcentral.com/articles/10.1186/s12872-021-01878-x

VII. Leishman, S. J., Do, H. L., & Ford, P. J. (2010). Cardiovascular disease and the role of oral bacteria. Journal of oral microbiology, 2, 10.3402/jom.v2i0.5781. https://doi.org/10.3402/jom.v2i0.5781

VIII. Lusis A. J. (2000). Atherosclerosis. Nature, 407(6801), 233–241. https://doi.org/10.1038/35025203

IX. “Oral Health.” World Health Organization, www.who.int/health-topics/oral-health#tab=tab_1 Accessed 14 May 2023.

X. Pahwa R, Jialal I. Atherosclerosis. [Updated 2022 Aug 8]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2023 Jan-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK507799/

XI. Shmerling, R. H. (2021, April 22). Gum disease and the connection to heart disease. Harvard Health. Retrieved April 23, 2023, from https://www.health.harvard.edu/diseases-and-conditions/gum-disease-and-the-connection-to-heart-disease#:~:text=The%20bacteria%20that%20infect%20the,attack%20and%20stroke%20may%20follow

XII. The Link Between Gum Disease and Heart Disease. Pennmedicine.org. (2022, May 24). Retrieved April 23, 2023, from https://www.pennmedicine.org/updates/blogs/heart-and-vascular-blog/2019/march/gum-disease-and-heart-disease

XIII. Zhang, Jiaqi, et al. “The Effects of Porphyromonas Gingivalis on Atherosclerosis-Related Cells.” Frontiers in Immunology, 23 Dec. 2021, www.ncbi.nlm.nih.gov/pmc/articles/PMC8734595/#:~:text=In%20the%20past%20few%20years,101

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How to Cite

Yuju Cheon. (2023). WHAT IS THE CONNECTION BETWEEN ORAL HEALTH & CARDIOVASCULAR DISEASES?. International Education and Research Journal (IERJ), 9(6). Retrieved from https://ierj.in/journal/index.php/ierj/article/view/2796