“FLOURIDE AFFECTING SPERM MOTILITY AND COUNT OF MALE Mus musculus”
Keywords:
fluoride, motility, sperm count, toxicity, infertilityAbstract
Fluoride being common non-biodegradable and long lasting contaminant that causes major health hazards are difficult to treat at low levels of pollution. The World Health Organisation (WHO) warn the use of flouride upto 1.5 ppm as upper limit in drinking water. Fluoride greatly affect male reproductive system by inhibiting sperm function and motility. It interrupts acrosomal reaction and capacitation, affecting quantity and quality of sperm. The present study has aimed to investigate the effect of inorganic pollutant, fluoride in sperm count and motility. Male mice were divided into two groups consisting of 10 animals in each group. The first group was served as control providing with normal water the second group were treated with 2ppm sodium fluoride in water with the help of gavage, for 30 days at the interval of 24 hours. The present study demonstrates the fluoride showing a significant decrease and harmful effects in sperm count and motility.
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