Samer Talib


We describe a highly unusual case of solitary rectal ulcer syndrome in a 90 years old African American female patient with a history of distal sigmoid colon resection for colon cancer with hysterectomy for uterine cancer. This patient presented with constipation, abdominal discomfort. Rectal showed positive fecal occult blood test. This finding raised suspicion for a possible recurrent malignancy.  Colonoscopy shows the presence of an ulcerative rectal lesion. Histopathology study of the Biopsy showed granulomatous lesion with no evidence of neoplastic tissue.

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Tjandra JJ, Fazio VW, Church JM, Lavery IC, Oakley JR, Milsom JW. The clinical conundrum of solitary rectal ulcer. Dis Colon Rectum 1992;35:227-34.

Preston DM, Lennard-Jones JE. Anismus in chronic constipation. Dig Dis Sci 1985;30:413-8.

Lam TCF, Lubowski DZ, King DW. Solitary rectal ulcer syndrome. Clinic Gastroenterol 1992,6:129-43.

Ming Sun w, et al. A common pathophysiology for full-thickness rectal prolapsed, anterior mucosal prolapsed and SRUS. Br J Surg 1989, 78:290-J

Mackle EJ, Parks TG. The pathogenesis and pathophysiology of rectal prolapsed and SRUS. Clin Gastroenterol 1986;15(4):985-1000.

Madigan MR, Morson BC. Solitary ulcer of the rectum. Gut1969;10:871-81

Tendler DA, Aboudola S, Zacks JF, O'Brien MJ, Kelly CP. Prolapsing mucosal polyps: An underrecognized form of colonic polyp-A clinicopathological study of 15 cases. Am J Gastroenterol 2002;97:370-6

Warren BF, Dankwa EK, Davies JD. "Diamond-shaped" crypts and mucosal elastin: Helpful diagnostic features in biopsies of rectal prolapse. Histopathology 1990;17:129-34.

Lonsdale RN. Microvascular abnormalities in the mucosal prolapse syndrome. Gut 1993;34:106-9

Chiang JM, Changchien, CR, Chen JR. Solitary rectal ulcer syndrome an endoscopic and histological presentation and literature review. Int J Colorectal Dis 2006;21:348-56.

Felt-Bersma RJ, Tiersma ES, Cuesta MA. Rectal prolapse, rectal intussusception, rectocele, solitary rectal ulcer syndrome, and enterocele. Gastroenterol Clin North Am. 2008;37:645–668, ix. [PubMed] [Google Scholar]

Cruveihier J Ulcer Chronique du rectum. In: Bailliere JB. Anatomie pathologique du crops human. Paris: 1829. [Google Scholar]

Madigan MR, Morson BC. Solitary ulcer of the rectum. Gut. 1969;10:871–881. [PMC free article] [PubMed] [Google Scholar]

Rutter KR, Riddell RH. The solitary ulcer syndrome of the rectum. Clin Gastroenterol. 1975;4:505–530. [PubMed] [Google Scholar]

Martin CJ, Parks TG, Biggert JD. Solitary rectal ulcer syndrome in Northern Ireland. 1971-1980. Br J Surg. 1981;68:744–747. [PubMed] [Google Scholar]

Tandon RK, Atmakuri SP, Mehra NK, Malaviya AN, Tandon HD, Chopra P. Is solitary rectal ulcer a manifestation of a systemic disease? Clin Gastroenterol. 1990;12:286–290. [PubMed] [Google Scholar]

Tjandra JJ, Fazio VW, Church JM, Lavery IC, Oakley JR, Milsom JW. The clinical conundrum of solitary rectal ulcer. Dis Colon Rectum. 1992;35:227–234. [PubMed] [Google Scholar]

Burke AP, Sobin LH. Eroded polypoid hyperplasia of the rectosigmoid. Am J Gastroenterol. 1990;85:975–980. [PubMed] [Google Scholar]

Ignjatovic A, Saunders BP, Harbin L, Clark S. Solitary ‘rectal’ ulcer syndrome in the sigmoid colon. Colorectal Dis. 2010;12:1163–1164. [PubMed] [Google Scholar]

Bonnard A, Mougenot JP, Ferkdadji L, Huot O, Aigrain Y, De Lagausie P. Laparoscopic rectopexy for solitary ulcer of rectum syndrome in a child. Surg Endosc. 2003;17:1156–1157. [PubMed]

Sharara AI, Azar C, Amr SS, Haddad M, Eloubeidi MA. Solitary rectal ulcer syndrome: endoscopic spectrum and review of the literature. Gastrointestinal Endoscopy. 2005;62:755–762. [PubMed] [Google Scholar]

Dehghani SM, Malekpour A, Haghighat M. Solitary rectal ulcer syndrome in children: a literature review. World J Gastroenterol. 2012;18:6541–6545. [PMC free article] [PubMed] [Google Scholar]

Suresh N, Ganesh R, Sathiyasekaran M. Solitary rectal ulcer syndrome: a case series. Indian Pediatr. 2010;47:1059–1061. [PubMed] [Google Scholar]


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