ALTERATIONS IN ENZYME PARAMETERS IN SCORPION HETEROMETROUS FULVIPES WITH EXPOSURE TO SELECTED HEAVY METALS: MERCURY AND LEAD

Authors

  • Prof. M.V Raghavendra Rao MD (US), Ph.D, FRSTMH (UK), FRSB (UK), FZSL (UK), FABAP, FSAB, FAGE Professor of Microbiology and Immunology, Dean of Student Affairs & Research Director, Avalon University School of Medicine (AUSOM), Sta. Rosaweg 122-124, Willemstad, Curaçao.
  • Yogesh Acharya Avalon University School of Medicine, Willemstad, Curacao.
  • Samir Fatteh Avalon University School of Medicine, Willemstad, Curacao.
  • Sireeshabala A Avalon University School of Medicine, Willemstad, Curacao.
  • Simi Paramban Avalon University School of Medicine, Willemstad, Curacao.
  • Jithender Kumar Naik Osmania University, Hyderabad, Telangana, India.
  • Anush C Pawar Osmania University, Hyderabad, Telangana, India.
  • Jayalakshmi G Gandhi Medical College, Hyderabad, India.
  • Amin Fateh Avalon University School of Medicine, Willemstad, Curacao.

Keywords:

Metals, Heavy, Toxicity, Animal models, Enzymes, Activity

Abstract

Heavy metal exposures in animals have various effects in metabolism of with alteration in biochemical constituents and enzyme levels. It is necessary that we documented heavy metals toxicities and take an appropriate precaution in mother and fetus to decrease its detrimental effects. An experimental study was performed with viviparous animal Heterometrous fulvipes to access the cumulative effect of chronic heavy metals, mercury and lead, exposure on the activity levels of the enzymes succinate dehydrogenase (SDH) and glutamate dehydrogenase (GDH). Chronic heavy metal exposure resulted in variation in the enzymes levels with increase in SDH and decreases in GDH in animal models, prompting a further study to consolidate the finding in human study.

References

Kulkarni BG, Kulkarni RG. Effect of Mercury exposure on enzymes in the clam Katelysia opima, J. Mar. Sci. 1987; 16 (4): 265-266.

Reddy R, Kumar V, Chari N. Effect of sub lethal concentration of mercury and copper on the AAT,ALAT and GDH of fresh water mussel, Parreysia rugosa. J. Environ. Biol. 1987; 6 (2): 67-70.

Sastry, Sarma. Effect of Mercuric chloride on the activities of brain enzymes in the Heteropneustus fossils. Mastya. 1981; 7: 66-69.

Sastry KV, Rao DR. Effect of mercuric chloride on some biochemical and physiological parameters of the freshwater murrel, Channa punctatus. Environ Res. 1984; 34(2):343-50.

Rani S, Gupta RK, Rani M. Heavy metal induced toxicity in Fish with Special Reference to Zinc and Cadmium. Int. J. of fisheries and aquatic studies. 2015; 3 (2):118-123.

Sastry KV, Sukla V. Effect of Cadmium on the rate of Oxygen up takes by fish channapunctatus. J. Environ. 1993; 5 (4):295-298.

Shakoori AR, Iqbal MJ, Mughal AL, Ali SS .Biochemical changes induced by inorganic mercury on the blood, liver and muscles of fresh water Chinese grass carp, Ctenopharyngodonidella, J. Exotoxic Environ. Monitory. 1996; 50 (6):429-434.

Santhana V, Azariah J. Effect of Copper chloride on the enzyme activities of the crab Sesarmaquadratum. Turk. J. Zoo. 2003; 27: 253-256.

Sastry KV, Sunnitha. Chronic toxic effects of chromium in Chenna punctatus. J. Environ. Biol. 1984: (5)1:47-52.

Tirumavalavan R. Effect of Cadmium on Biochemical parameters in fresh water fish Oreochromis mossambicus. Asia. J. Sci. Tech. 2010; 4:100-104.

Oner M, Atli G, Canli M. Changes in serum parameters of fresh water fish Oreochromis niloticus following prolonged metal (Ag, Cd, Cr, Cu, Zn) exposures. Environ Toxicol Chem. 2008; 2:360-366.

Rao MVR et. al. Effect of Mercury and lead on the maternal animal and the embryonic development of viviparous scorpion Heterometrous fulvipes during the gestation period. Thesis submitted in partial fulfillment for the Degree of Doctor of Philosophy, Nagarjuna University, AP, India, 1991.

Rajanna B, Chapatwala KD, Vaishnav D, Desaiah D. Change in ATPase activities in tissues of rats fed on Cadmium. J. Environ. Biol. 1981; 2 (1):1-9.

Fig-40: Effect of mercury and lead on the activity levels of glutamate dehydrogenase in the hepatopancreas of H. fulvipes during the gestation period.

Fig-41: Effect of mercury and lead on the activity levels of glutamate dehydrogenase in the pedipalpal muscle of H. fulvipes during the gestation period.

Fig-42: Effect of maternal treatment with mercury and lead on the activity levels of glutamate dehydrogenase in the embryos of H. fulvipes during the gestation period.

Fig-43: Effect of mercury and lead on the activity levels of succinic dehydrogenase in the hepatopancreas of H. fulvipes during the gestation period.

Fig-44: Effect of mercury and lead on the activity levels of succinic dehydrogenase in the pedipalpal muscle of H. fulvipes during the gestation period.

Fig-45: Effect of maternal treatment with mercury and lead on the activity levels of succinic dehydrogenase in the embryos of H. fulvipes during the gestation period.

Additional Files

Published

15-07-2017

How to Cite

Prof. M.V Raghavendra Rao, Yogesh Acharya, Samir Fatteh, Sireeshabala A, Simi Paramban, Jithender Kumar Naik, Anush C Pawar, Jayalakshmi G, & Amin Fateh. (2017). ALTERATIONS IN ENZYME PARAMETERS IN SCORPION HETEROMETROUS FULVIPES WITH EXPOSURE TO SELECTED HEAVY METALS: MERCURY AND LEAD. International Education and Research Journal (IERJ), 3(7). Retrieved from https://ierj.in/journal/index.php/ierj/article/view/1222

Issue

Vol. 3 No. 7 (2017): JULY ISSUE, INTERNATIONAL EDUCATION AND RESEARCH JOURNAL

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Articles

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