X-RAY STUDY OF 1-TOSYL-2- ETHYL PYRROLIDINE TO DETERMINE ITS INCLINATION ANGLE µN, SHIFT IN SCREEN SETTING SN, ABSORPTION COEFFICIENT µ AND SPACE GROUP

Mohd Iqbal Raina

Abstract


Alkaloids usually have complex structure with nitrogen atom involved in the heterocyclic ring. At present more than two thousand alkaloids are known. Broadly alkaloids have been classified into various groups namely Pyrrolizidines alkaloids, Pthalideisoquinoline alkaloids and Pyrrolidine alkaloids. Among these the pyrrolidine alkaloids have been undertaken in the laboratory of department of physics in Jammu University for their crystal analysis. The crystal analysis of 1-TOSYL-2- ETHYL PYRROLIDINE alkaloids was done using oscillation method, Rotation Method and Weissenberg Method.  By using all these methods cell parameters like Equi-inclination Angle (µn), Shift in screen setting (Sn) of Weissenberg photograph, linear absorption coefficient (µ) and Space Group were calculated in this study using X-ray diffraction techniques. Density of the compound was determined by floatation technique. The values of µn corresponding to layer line Number 1, 2 and 3 of Weissenberg photograph were found to be 2.984, 5.972 and 8.967 respectively and Sn for the same layer lines were 1.264mm, 2.538mm and 3.826mm respectively. The value of µ and Space Group were found to be 20.941cm-1 and P21212, P212121 respectively. Density of the compound under investigation was found out to be 1.314 gm/cc and was in close agreement with observed density which was 1.309 gm/cc. It was concluded in the research that Unit cells of Pyrrolidine Alkaloids belong to ORTHORHOMBIC crystal system.

Keywords


ORTHORHOMBIC, 1-TOSYL-2-ETHYLPYRR0LIDINE, Weissenberg photograph, Linear Absorption Coefficient, Inclination Angle, Space Group, Pyrrolidine Alkaloids

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