DILEMMAS OF LIFE AND DEATH WITH CYANIDE TOXICITY

Authors

  • Dr. Raghavendra Rao M. V. Scientist Emeritus, Director of Research Laboratory, Apollo Institute of Medical Sciences and Research, Hyderabad, TS, India
  • Dr. Mallem Dinakar Professor, Department of Forensic Medicine, Apollo Institute of Medical Sciences and Research, Hyderabad, TS, India
  • Dr. Mohammed Ismail Nizamil Associate Professor, Department of Emergency,Medicine, Nizam's Institute of Medical Sciences, Hyderabad,TS, India,
  • Dr. Sumana Sen Professor and Head, Department of Pharmacology, Apollo Institute of Medical Sciences and Research, Hyderabad, TS, India
  • Dr. Mary Sowjanya Senior President, Department of Forensic Medicine and Toxicology AIIMS, Bibinagar, Hyderabad, TS, India
  • Dr. Harika Department of Anesthesia, Alluri Seetharama Raju Academy of Medical Sciences(ASRAM) Eluru, AP, India
  • Dr. N. Uday Goutam Consultant Neurosurgeon, Gowtam Neurocare, 261 MIG, KPHB Colony, Road no-4, Kukatpally, Hyderabad, Telangana
  • Dr. M.V. Nagabhushanam Professor and Principal, Hindu College of Pharmacy, Guntur, AP, India
  • Dr. Rajkumar Kudari Professor, Department of Pharmaceutical Analysis, Hindu College of Pharmacy, Guntur, AP, India
  • Dr. Sridhar Reddy Peddi Professor of Medicine and Cardiology, Apollo Institute of Medical Sciences and Research, Hyderabad, TS, India

Keywords:

Hydroxocobalamin, Hydrocyanic Acid (HCN), Sodium Cyanide (NaCN), Potassium Cyanide (KCN), Cytochrome Oxidase

Abstract

Cyanide is one of the oldest poisons. Large doses of cyanide prevent cells from using oxygen and eventually these cells die. The heart, respiratory system and central nervous system are most susceptible to cyanide. Cyanide directly stimulates the chemo-receptors of the carotid and aortic bodies that results in hyperpnoea. Cardiac irregularities are often noted, but the heart invariably outlasts the respirations. The central origin of death is due to respiratory arrest. Hydrocyanic acid (HCN), sodium cyanide (NaCN) and potassium cyanide (KCN) or cyanogen are very potent, extremely lethal and most rapidly fatal. Poisoning with hydrocyanic acid is almost always fatal because of the low fatal dose and the rapidity with which it acts.

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Additional Files

Published

15-09-2023

How to Cite

Dr. Raghavendra Rao M. V., Dr. Mallem Dinakar, Dr. Mohammed Ismail Nizamil, Dr. Sumana Sen, Dr. Mary Sowjanya, Dr. Harika, Dr. N. Uday Goutam, Dr. M.V. Nagabhushanam, Dr. Rajkumar Kudari, & Dr. Sridhar Reddy Peddi. (2023). DILEMMAS OF LIFE AND DEATH WITH CYANIDE TOXICITY. International Education and Research Journal (IERJ), 9(9). Retrieved from http://ierj.in/journal/index.php/ierj/article/view/3039

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