EARLY ONSET OF ADRENAL INSUFFICIENCY IS ASSOCIATED WITH WORSE OUTCOMES
Keywords:
Primary adrenal insufficiency, Adrenal tuberculosis, Mineralocorticoids, kanamycin, amikacin, capreomycinAbstract
Tuberculosis is adopted to be a critical action of Addison's disease and acute adrenal failure worldwide.Addison’s disease is rare but serious adrenal gland disarray. As a result, the adrenal gland can't process cortisol and aldosterone hormones. Thomas Addison was the first to describe Addison's disease in 1855. He showed that tuberculosis (TB) destroyed the bilateral adrenal glands in six cases. Mycobacterium tuberculosis infection is the most common cause of adrenal failure in those with adrenal TB. Bilateral adrenal glands are more commonly affected by adrenal tuberculosis than unilateral glands. Patients with Primary Adrenal Insufficiency due to Adrenal TB require lifelong replacement of Glucocorticoids and Mineralocorticoids. Tuberculosis (TB) is the leading cause of adrenal insufficiency in resource-limited settings. Adrenal infections are an important but under-recognized clinical entity.Differentiating between tuberculosis Addison's disease and other types of adrenal insufficiency can be done with a computed tomography (CT) scan or magnetic resonance imaging (MRI).
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