• Aishwarya Tushar Pandit Department of Biotechnology, R C Patel College, Shirpur, Dhule, Maharashtra, India
  • D. Sreenivasa Rao Department of Biotechnology, Nagarjuna University, Guntur, AP, India.
  • K. L. Prathyusha Department of Dental Sciences, SIBAR Institute of Dental Sciences, Guntur, AP, India
  • Yogendra Verma Department of Microbiology, Mandsaur University, Mandsaur, Madhya Pradesh, India
  • Nikita Chitrapu Department of genetics, Shadan degree and PG College for women, Khairatabad, Hyderabad, TS, India
  • Ritika Chitrapu Department of genetics, Shadan degree and PG College for women, Khairatabad, Hyderabad, TS, India
  • Dilip Mathai Department of Medicine, Dean, Apollo Institute of Medical Sciences and Research, Jubilee Hills, Hyderabad, Telangana, India
  • Prof Dr M.V. Raghavendra Rao Department of Medicine, Apollo Institute of Medical Sciences and Research, Jubilee Hills, Hyderabad, Telangana, India


Body mass index (BMI), Syndromic obesity, Monogenic Forms of Obesity


Obesity is a heritable trait influenced by genetics, epigenetic, and the environment Obesity is a universal epidemic and is devoted to global morbidity and mortality interfered via the improvement of fatty liver disease, type 2 diabetes (T2D), cardiovascular (CVD), and other diseases. It is an aftereffect of an uplifted caloric absorption, an inactive lifestyle, and a genetic, as well as an epigenetic susceptibility Obesity, is a condition that affects human health adversely. Obesity is a common disease caused by multiple factors. It has been reported heredity plays a strong role in obesity development. Because of this complex, multifactorial pattern, diseases and traits such as obesity are called complex genetic traits. There are sequences of variants present in the population that increases or decreases an individual’s risk for obesity in their environment. Gene involves in the development of common forms of obesity, thereby identifying pathways that are causal in patients, will guide clinicians and scientists in designing more effective therapies and in identifying high-risk individuals for early intervention. This is inconsistent with the absence of strong signatures of selection at single nucleotide polymorphisms (SNP’S) linked to obesity. Most SNPs are identified by comparing two chromosomes that are common and shared throughout the world: 90% of such SNPs will be seen again at a frequency of at least 1%. Most of these common variants probably have no functional consequence and are essentially the equivalent of genetic dialect or random differences in spelling with no real significance.


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How to Cite

Aishwarya Tushar Pandit, D. Sreenivasa Rao, K. L. Prathyusha, Yogendra Verma, Nikita Chitrapu, Ritika Chitrapu, Dilip Mathai, & Prof Dr M.V. Raghavendra Rao. (2021). IS GENETIC OBESITY A BOON OR BANE?. International Education and Research Journal (IERJ), 7(12). Retrieved from

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