TRICHINELLA SPIRALIS BREAKOUTS IN THE BUENOS AIRES, ARGENTINA PROVINCE. A PENDING SOLUTION MATTER
Keywords:
Epidemic outbreaks, Trichinosis, ELISA, IIF, PatientsAbstract
The following work conducts a research about three trichinosis outbreaks that took place in the province of Buenos Aires, Argentina in the year 2016. An inquiry was made to determine the risk factors associated with the epidemic outbreaks. The products elaborated with pig meat coming from the presumably infested swine, an enzymatic digestion was performed in order to find the cause of the outbreaks in humans. All the patients that stated they had consumed meat products elaborated from presumably infected animals and presented any symptoms, were included in the study. Two techniques for antibody detection in patients serum were used; IFI and ELISA. Furthermore, an antigen detection technique that allowed to determine the infection before the antibody determination studies, was evaluated.
It is propound to include major sensibility and specificity techniques that allow an efficient and quick diagnose in epidemic outbreaks. At the same time, improve the sanitary education among population with a view to avoid the ingestion of uncertified meat or sub products.
References
Calcagno MA, Bourlot I, Taus R, Saracino MP & Venturiello SM (2014). Description of an outbreak of human trichinellosis in an area of Argentina historically regarded as Trichinella free: the importance of surveillance studies. Veterinary Parasitology. 200: 251-256.
Darwin Murrell K & Pozio E (2011). Worldwide occurrence and impact of human trichinellosis, 1986–2009.Emerging Infectious Diseases 17: 2194–2202.
De-la-Rosa-Arana JL, Campos-Rodríguez RV, Rivera-Aguilar V, Escobar-Gutierrez A, Millar-Garcia A, Herrera-Gonzalez NE & Jarillo-Luna A (2012). Comparative effects of levamisole, Staphylococcus and Freund´s adjuvant on rat immunization with excretory and secretory antigens of Trichinella spiralis muscle larvae. Parasitology Research. 111: 1599-1605.
Dupoy-Camet, J, Kociecka W, Bruschi F, Bolas-Fernandez F & Pozio, E (2002). Opinion on the diagnosis and treatment of human trichinellosis. Expert Opinion on Pharmacotherapy3: 1117-1130.
Gamble HR, Bessonov AS, Cuperlovic K, Gajadhar AA, Van Knapen F, Noeckler K, Schenone H & Zhu X (2000). International Commission on Trichinellosis: recommendations on methods for the control of Trichinella in domestic animals intended for human consumption. Veterinary Parasitology 93: 393-408.
Gottstein B, Pozio E & Nockler, K (2009). Epidemiology, diagnosis, treatment and control of trichinellosis. Clinical Microbiology Review. 22: 127-145.
Kociecka W (2000). Trichinellosis: human disease, diagnosis and treatment. Veterinary Parasitology 93: 365-383.
Liu RD, Jiang P, Wen H, Duan JY, Wang LA, Li JF, Liu CY, Sun GG, Wang ZQ & Cui J. (2016). Screening and characterization of early diagnostic antigens in excretory secretory proteins from Trichinella spiralis intestinal infective larvae by inmunoproteomics. Parasitology Research. 115: 615-622.
Liu XL, Ren HN, Shi YL, Hu CX, Song YY, Duan JY, Zhang HP, Du XR, Liu RD, Jiang P, Wang ZQ & Cui J (2017). Early detection of Trichinella spiralis DNA in the feces of experimentally infected mice by using PCR. Acta Tropica 166: 351-355.
O'Connell EM & Nutman TB (2015). Eosinophilia in Infection Disease. Immunology and Allergy Clinics of North America. 35:493-522.
Ortega-Pires G, Vaquero-Vera A, Fonseca-Liñan R, Bermudez- Cruz RM, & Arguello-Garcia, R (2015). Induction of protection in murine experimental models against Trichinella spiralis: an up-to-date-review. Journal of Helminthology .89: 526-539.
Pozio E, & Darwin Murrel, K (2006). Systematics and epidemiology of Trichinella. Advances in Parasitology. 63: 367-439.
Ribicich M, Gamble HR, Rosa A, Bolpe J, & Franco A (2005). Trichinellosis in Argentina: an historical review. Veterinary Parasitology 132: 137-142.
Sharma RK, Raghavendra N, Mohanty S, Tripathi, BK, Gupta B, & Goel A (2014). Clinical and biochemical profile of trichinellosis outbreak in north India. Indian Journal of Medical Research 140: 414–419.
Sun GG, Liu RD, Wang ZQ, Jiang P, Wang L, Liu XL, Liu CY, Zhang X, & Cui J( 2015). New diagnostic antigens for early trichinellosis: the excretory secretory antigens of Trichinella spiralis intestinal infective larvae. Parasitology Research. 114: 4637-4644.
Wang L, Wang ZQ, Hu DD & Cui J (2013) Proteomic analysis of Trichinella spiralis muscle larval excretory-secretory proteins recognized by early infection sera. BioMed Research International 2013, Article ID 139745, 7 pages, http://dx.doi.org/10.1155/2013/139745
Wang ZQ, Liu RD, Sun GG, Song YY, Jiang P, Zhang X, & Cui J (2017). Proteomic analysis of Trichinella spiralis adult worm excretory- secretory proteins recognized by sera of patients with early trichinellosis. Frontiers in Microbiology 8, 986, doi 10.3389/fmicb.2017.00986.
Xue B, Xiaoxiang H, Xiaolei L, Bin, T, & Mingyuan L (2017).Current research of trichinellosis in China. Frontiers in Microbiology 8, 1472, doi 10.3389/fmicb
Yang Y, Cai YN, Tong MW, Sun N, Xuan YH, Kang YJ, Vallee I, Boireau P, Cheng SP, & Liu MY (2016) Serological tools for detection of Trichinella infection in animals and humans. One Health. 4: 25-30.
Zumaquero-Rios JL, Garcia-Juarez J, De-la-Rosa-Arana JL, Marcet R, & Sarracent-Perez J (2012) Trichinella spiralis: monoclonal antibody against the muscular larvae for the detection of circulating and fecal antigens in experimentally infected rats. Experimental Parasitology. 132: 444-449
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