B. Sandhya , M. V. Raghavendra Rao , M. Raghu Ram , Sireesha Bala A. , Samir Fatteh , Reshma Fateh


The testosterone therapy in male patients has become clinical interest now days. Although there are a number of potential benefits of male testosterone replacement therapy, but yet there have not been any controlled trials of this therapy for type-2 diabetes. In present study we investigate the effect of testosterone replacement therapy by discussing a limited number of trials initially. The study was carried out with 70 hypogonadic patients at the age of 40 to 60 years selected from Life hospital situated in Guntur. Patients with the serum levels <200ng/dl were given 80mg Andriol orally and to patients with testosterone >200ng/dl were given 40mg/day was administered orally for 6 months to the male patients. The biochemical test and level of hormonal in blood was tested before the treatment, after three months and six months of the treatment.   Initially the average testosterone level  (204 ng/dl) were increased approximately two times (452 ng/dl) after six months of treatment. Hence, we found that testosterone therapy fasting blood glucose, postprandial glucose and glycosylated hemoglobin (HB1AC) reduced significantly. Therefore, the testosterone replacement therapy might have the beneficial effects on treating type-2 diabetes.


Testosterone, Diabetes, Hypogonadism.

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