EFFECT OF PERIODONTAL THERAPY ON PREGNANCY OUTCOME IN WOMEN SUFFERING FROM CHRONIC PERIODONTITIS- A PROSPECTIVE CASE-CONTROL STUDY

S. Tanneeru , B. V. Ramesh Reddy , V. K. Chava , V. Sita Lakshmi

Abstract


Background: Recent studies have shown periodontal diseases as risk factors for adverse pregnancy outcomes, such as preterm births and low birth weight.

Aim: The present study was designed to determine the effect of non-surgical periodontal therapy on pregnancy outcomes, in women with periodontitis and to detect IgM status in cord blood during delivery.

Design, Materials & Methods; 100 pregnant women with chronic generalized periodontitis in their 2nd trimester were selected and recruited for the study. They were grouped in to two: Treatment group Non-Treatment group. Periodontal parameters of all the subjects were recorded at baseline and after delivery. Data related to weight of infant and type of delivery was recorded. During the delivery, cord blood was collected for the estimation of IgM antibodies. All the recordings were subjected for statistical analysis.

ResultS and Conclusion: The results of the present study evidenced association between maternal periodontitis and adverse pregnancy outcomes.


Keywords


chronic periodontitis, adverse pregnancy outcomes, preterm birth, low birth weight, maternal infections, non surgical periodontal therapy.

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References


B. V. Ramesh Reddy , S. Tanneeru & V. K. Chava.2014. The effect of phase-I periodontal therapy on pregnancy outcome in chronic periodontitis patients. Journal of Obstetrics and Gynaecology, January 34: 29– ;32.

Marcela Yang Hui Zi,1 Priscila Larcher Longo,1 Bruno Bueno-Silva,1 and Marcia Pinto Alves Mayer1,* Mechanisms Involved in the Association between Periodontitis and Complications in Pregnancy. Front Public Health. 2015 Jan 29;2:290.

Moneet Walia, Navdeep Saini 2015 Relationship between periodontal diseases and preterm birth: Recent epidemiological and biological data. Int J Appl Basic Med Res. 2015 Jan-Apr; 5(1): 2–6.

Tarannum F and Faizuddin MD.2007. Effect of periodontal therapy on pregnancy outcome in women affected by periodontitis. Journal of Periodontology 78:2095-2103.

Fouzia Tarannum, Shiva Prasad RK, Shobha R, Santosh Kumar BB, Supriya Ebenezer. 2015. Awareness of the association between periodontal disease and adverse pregnancy outcome among the general female Population. Indian Journal of Dental Research, 26(1), pg 21-25.

Page RC. 1991. The role of inflammatory mediators in the pathogenesis of periodontal disease. Journal of Periodontol Research 26:230-242.

Contreas A, Herra JA, Soto JE et al.2006. periodontitis is associated with preeclampsia in pregnant women. Journal of Periodontology. 77:182-188.

Barak S, Barack OO, Machtei EE, Sprecher H and Ohel G. 2007. Evidence of periopathogenic microorganisms in placentas of women with preeclampsia. Journal of Periodontology 78:670-676.

Fernanda MS, Miranda LOC, Jose EC et al. 2008. Maternal periodontitis as a potential risk variable for preeclampsia: A case-control study. Journal of Periodontology 79:207-215.

Heather J, Bogess KA, Kevin M et al. 2009. Fetal exposure too oral pathogens and

subsequent risk to oral pathogens and subsequent risk for neonatal intensive care admission.

Journal of Periodontology 80:878-883.

Simone RA, Henri T and Jean-Luc D. 2010. Periodontal diseases, preterm births, and low birth weight: Findings from a homogenous cohort of women in Madagascar Journal of Periodontology 81:205-213.

Mathew RJ, Bose A, Prasad JH, Muliyil JP, Singh D. Maternal periodontal disease as a significant risk factor for low birth weight in pregnant women attending a secondary care hospital in South India: a case-control study. Indian J Dent Res. 2014 Nov-Dec;25(6):742-7.

Tellapragada C, Eshwara VK, Acharya S, Bhat P, Kamath A, Vishwanath S, Mukhopadhyay C. Prevalence of Clinical Periodontitis and Putative Periodontal Pathogens among South Indian Pregnant Women. Int J Microbiol. 2014;2014:420149

Michalowicz BS, Novak MJ, James SH et al. 2009. Serum inflammatory mediators in pregnancy: changes after periodontal treatment and association with pregnancy outcomes. Journal of Periodontology 80:1731-1741.

Bryan S. Michalowicz, James S. Hodges, M. John Novak, William Buchanan, Anthony J. DiAngelis, Panos N. Papapanou, Dennis A. Mitchell, James E. Ferguson, Virginia R. Lupo, James Bofill, Stephen Matseoane. 2010Change in Periodontitis during Pregnancy and Risk of Preterm Birth and Low Birthweight. J Clin Periodontol.

Hongyu ren and Minquan Du. 2017.Role of maternal periodontitis in preterm birth. Frontiers in immunology. 8:139-149.

Ageuda A, Ramon JM, Manau C, Guerrero A and Echeverria JJ. 2008. Periodontal Disease as a risk factor for adverse pregnancy outcomes: a prospective cohort study. Journal of Clinical Periodontology 35:16-22.

Wimmer G, Pihlstrom BL. 2008. A critical assessment of adverse pregnancy outcome and periodontal disease. Journal of Clinical Periodontology 380-397.

Bassani DG, Olinto MTA and Kreiger N. 2007. Periodontal disease and perinatal outcomes: a case-control study. Journal of Clinical Periodontology 34:31-39.

Jae-In Ryu, Kyung-Joon Oh, Hye-Jin Y et al. 2010. Health behaviours, periodontal

conditions, and periodontal pathogens in spontaneous preterm births: A case-control study in Korea. Journal of Periodontology 82:855-863.

Moore S, Randhawa M and Ide M. 2005. A Case-Control study to investigate an association between adverse pregnancy outcome and periodontal disease. Journal of Clinical Periodontology.32:1-5.

Lopez NJ, Smith PC and Gutierrez J. 2002. Periodontal Therapy May Reduce the Risk of Preterm Trial. Journal of Periodontology 73: 911-924

Issac SGF, Simone SC, Maria da CNC et al. 2010. Periodontal therapy and low birth weight: preliminary results from an alternative methodological strategy. Journal of Periodontology 81:1725-1733.

Offenbacher S, Dongming L, Robert S. 2006. Effects of periodontal therapy during pregnancy on periodontal status, biologic parameters, and pregnancy outcomes: a pilot study. Journal of Periodontology 77:2011-2024.

Jeffcoat MK, Huath JC, Geurs NC et al. 2003. Periodontal disease and preterm birth: results of a pilot intervention study. Journal of Periodontology 74:1214-1218.

Michalowicz BS, Hodges JS and DiAngelis AJ.2006. Treatment of periodontal disease and the risk of preterm birth. N Engl J Med 355:1885-1894

Madianos PN, Lieff S, Murtha AP et al. 2001. Maternal periodontitis and prematurity. Part 2: Maternal infection and fetal exposure. Annals of Periodontology.6:175-182.

Jeffrey LE, Novak MJ, Bryan SM et al. 2009. Systemic Immune Response In Pregnancy And Periodontitis: Relationship To Pregnancy Outcomes In The Obstetrics And Periodontal Therapy (OPT) Study. Journal of Periodontology 80:953-960.

D’Aiuto F, Nibali L, Parker M, Suvan J Tonett MS. 2004. Short term effects of intensive periodontal therapy on serum inflammatory markers and cholesterol. Journal of Dental Research 84:269-273.


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