ALTERATIONS IN ENZYME PARAMETERS IN SCORPION HETEROMETROUS FULVIPES WITH EXPOSURE TO SELECTED HEAVY METALS: MERCURY AND LEAD

M.V Raghavendra Rao , Yogesh Acharya , Samir Fatteh , Sireeshabala A , Amin Fateh , Simi Paramban , Jithender Kumar Naik , Anush C Pawar , Jayalakshmi G

Abstract


Heavy metal exposures in animals have various effects in metabolism of with alteration in biochemical constituents and enzyme levels. It is necessary that we documented heavy metals toxicities and take an appropriate precaution in mother and fetus to decrease its detrimental effects. An experimental study was performed with viviparous animal Heterometrous fulvipes to access the cumulative effect of chronic heavy metals, mercury and lead, exposure on the activity levels of the enzymes succinate dehydrogenase (SDH) and glutamate dehydrogenase (GDH). Chronic heavy metal exposure resulted in variation in the enzymes levels with increase in SDH and decreases in GDH in animal models, prompting a further study to consolidate the finding in human study.


Keywords


Metals, Heavy, Toxicity, Animal models, Enzymes, Activity

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References


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